My name is Typhanie Dumontet, I joined Dr. Hammer's lab at the University of Michigan in 2018 as a post-doctoral research fellow, where I currently combine single-cell technology and newly developed mouse models to uncover transcriptional programs participating in adrenal differentiation.
I obtained a Master's Degree and a Ph.D. in Genetics and Physiology from Clermont-Auvergne University (France) in 2017.
In Dr. Martinez's lab, my thesis work aimed at investigating the cellular origin of adrenal hyperplasia caused by mutations in a PKA-related gene using genetic approaches of cell lineage in mouse specie (Dumontet et al., 2018_JCI Insight). I also performed in vitro and in vivo studies to understand the effects of PKA activation on global protein SUMOylation (Dumontet et al., 2019_FASEB). During my Ph.D. training, I became highly interested in the mechanisms that govern cell differentiation.
In 2018, I joined Dr. Hammer's lab at the University of Michigan as a post-doctoral research fellow, where I currently combine single-cell technology and newly developed mouse models to uncover transcriptional programs participating in adrenal differentiation. More broadly, I am particularly interested in understanding how the deregulation of these programs might contribute to pathologies in humans.
With Dr. Hammer as a mentor, my long-term goal is to develop the necessary training, skills, and experience to become an independent investigator by implementing new technology and mouse models to address pathologic and therapeutic challenges of adrenal diseases.