University of Michigan Medical School :: Postdoctoral Training

Goncalo Abecasis: We use new genomic technologies to study genetic variation and its impact on complex disease in humans.
Yonqun Oliver He: Microbiology, immunology, and bioinformatics
Maureen Sartor: Bioinformatics/statistical methods for integrative analysis and interpretation of 'omics data, especially in application to head and neck cancer
Thomas Wilson: The Wilson laboratory studies structural genome (in)stability and its relationship to double-strand break repair (dys)function using experimental manipulation of DNA repair proteins and global genomic/bioinformatic approaches.
Yang Zhang: Develop bioinformatics algorithms for protein structure prediction and structure-based drug discovery.

Zhan Chen: Molecular Level Understanding on Peptides and Proteins at Interfaces
Yali Dou: Epigenetic regulation in embryonic stem cells and cancer stem cells.
Greg Dressler: We use biochemical and genetic models to study how stem cells make adult tissues and organs.
Carol Fierke: Enzymology of posttranslational modifications and RNA processing
Renny Franceschi: The Franceschi lab studies transcriptional control mechanisms in bone with emphasis on extracellular matrix and mechanical signals.
Dan Goldman: Retina, optic nerve and motor neuron regeneration
Tom Kerppola: Roles of protein interactions and nucleoprotein complexes in development and disease
Patrick O'Brien: Mechanisms of DNA repair
Mark Saper: Structural and biochemical studies to understand how a newly identified lipoprotein regulates peptidoglycan synthesis in pathogenic bacteria.
Hisashi Umemori: Wiring the functional brain: specific synapse formation and activity-dependent synapse refinement
Yanzhuang Wang: Golgi Biogenesis, Function, and defects in diseases
Yang Zhang: Develop bioinformatics algorithms for protein structure prediction and structure-based drug discovery.

Zhan Chen: Molecular Level Understanding on Peptides and Proteins at Interfaces
Ajit Joglekar: We study the biophysics of macro-molecular machines.
Ronald Holz: Biophysics of exocytosis
Ayyalusamy Ramamoorthy: Role of amylin misfolding, zinc and insulin on type II diabetes.
Sivaraj Sivaramakrishnan: Molecular motors, FRET sensors, signal transduction in cardiomyocytes

David Beer: Gene Discovery and Characterization in Lung and Esophageal Cancer
Dean Brenner: Biomarkers for GI Cancer Early Detection
Ron Buckanovich: Study of cancer stem cells and the tumor vascular niche
Laura Buttitta: Cell cycle control in Drosophila and mammalian cancer cells
Maria Castro: Brain cancer biology, role of tumor ligands in hematopoietic stem cells' development, Toll receptor-mediated and STAT3 signaling; Development of novel therapeutic strategies.
Zora Djuric: Nutritional modualtion of biomarkers of cancer risk.
Yali Dou: Epigenetic regulation in embryonic stem cells and cancer stem cells.
Xing Fan: Brain cancer stem cells.
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Gary Hammer: Dr. Hammer’s lab combines classic molecular biology techniques and whole animal models to study adrenocortical development and dyregulation that leads to adrenocortical carcinoma.
Elizabeth Lawlor: Cancer and stem cell biology
Mats Ljungman: My lab studies mechanisms of gene expression and DNA repair and how these processes are altered in cancer cells
Pedro Lowenstein: We study the cellular, molecular and mathematical basis of cancer; stem cells, nanoparticles, and gene therapy are used in experimental models, and in early clinical trials in patients.
Ann Miller: We study the molecular mechanisms that regulate cytokinesis in normal cells and how this process may become mis-regulated in cancer
Patrick O'Brien: Mechanisms of DNA repair
Diane Robins: We study basic mechanisms of gene regulation in androgen-dependent prostate cancer and in sexually dimorphic liver gene expression, using mouse and cell models.
Maureen Sartor: Bioinformatics/statistical methods for integrative analysis and interpretation of 'omics data, especially in application to head and neck cancer
JoAnn Sekiguchi: My lab studies the mechanisms underlying maintenance of genome stabilty and the impact of defects in these processes on disease outcomes, including immunodeficiency, lung disease and tumorigenesis.
Sunny Wong: Roles of hair follicle stem cells in tissue homeostasis, wound healing and cancer.

Sharlene Day: We are interested in dysregulation of protein turnover in cardiomyopathies and expression patterns and consequences of mutant sarcomere genes in hypertrophic cardiomyopathy.
Doug Engel: Molecular genetics of blood disorders
Jose Jalife: Our work focuses on the understanding of the fundamental mechanisms of complex, life-threatening arrhythmias and sudden cardiac death
Daniel Lawrence: Studies of the neurovascular unit and cerebrovascular disease.
Benedict Lucchesi: Integrative cardiovascular research.
Jordan Shavit: We study the genetics of blood clotting disorders using zebrafish and mouse models.
Hector Valdivia: Cardiac Arrhythmias
Cristen Willer: Find novel genes and genetic variants underlying cardiovascular disease using genome and exome sequencing and high-throughput genotyping arrays

Peter Arvan: Diseases caused by abnormal protein trafficking in the secretory pathway
Markus Bitzer: MicroRNAs in kidney disease and aging
Maria Castro: Brain cancer biology, role of tumor ligands in hematopoietic stem cells' development, Toll receptor-mediated and STAT3 signaling; Development of novel therapeutic strategies.
Gyorgyi Csankovski: Epigenetic regulation of X-linked gene expression during C. elegans dosage compensation
Daniel Eitzman: To idenify and characterize novel mediators of atherosclerosis
Xing Fan: Brain cancer stem cells.
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Daniel Klionsky: Autophagy in yeast
Catherine Krull: Cell migrations during development
Mats Ljungman: My lab studies mechanisms of gene expression and DNA repair and how these processes are altered in cancer cells
Malcolm J. Low: Our lab investigates the neuroendocrine regulation of appetite, feeding behavior, metabolism and stress using mutant mice, neuroanatomical tracing, pharmacology, and behavioral assays.
Pedro Lowenstein: We study the cellular, molecular and mathematical basis of cancer; stem cells, nanoparticles, and gene therapy are used in experimental models, and in early clinical trials in patients.
Carey Lumeng: How inflammatory cells modify metabolism associated with obesity-related diseases.
Juanita Merchant: My lab focuses on the role of chronic inflammation in the GI tract as a trigger for gastric or colon cancer.
Ann Miller: We study the molecular mechanisms that regulate cytokinesis in normal cells and how this process may become mis-regulated in cancer
Jordan Shavit: We study the genetics of blood clotting disorders using zebrafish and mouse models.
Robert Thompson: microRNA Actions in the CNS
Eric White: Extracellular matrix biology in lung repair and regeneration
Bing Ye: Molecular and cellular mechanisms underlying neural circuit development in Drosophila

Renny Franceschi: The Franceschi lab studies transcriptional control mechanisms in bone with emphasis on extracellular matrix and mechanical signals.
Catherine Krull: Cell migrations during development

Ernesto Bernal-Mizrachi: Regulation of beta cell mass and diabets
Laura Buttitta: Cell cycle control in Drosophila and mammalian cancer cells
Maria Castro: Brain cancer biology, role of tumor ligands in hematopoietic stem cells' development, Toll receptor-mediated and STAT3 signaling; Development of novel therapeutic strategies.
Kathleen Collins: Our long term goals are to understand viral mechanisms for establishing persistent infections
Gyorgyi Csankovski: Epigenetic regulation of X-linked gene expression during C. elegans dosage compensation
Greg Dressler: We use biochemical and genetic models to study how stem cells make adult tissues and organs.
Doug Engel: Molecular genetics of blood disorders
Xing Fan: Brain cancer stem cells.
Philip Gage: Cell signaling pathways and transcriptional networks regulating eye development and disease
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Deborah Gumucio: Organogenesis of the intestine
Patrick Hu: We use C. elegans to study the molecular basis of aging and age-related disease
Ajit Joglekar: We study the biophysics of macro-molecular machines.
Alon Kahana: Neural crest development and craniofacial tissue regeneration.
Sundeep Kalantry: Epigenetics
Catherine Krull: Cell migrations during development
Daniel Lawrence: Studies of the neurovascular unit and cerebrovascular disease.
Jiandie Lin: Metabolic disease and mechanisms
Malcom J. Low: Our lab investigates the neuroendocrine regulation of appetite, feeding behavior, metabolism and stress using mutant mice, neuroanatomical tracing, pharmacology, and behavioral assays.
Ann Miller: We study the molecular mechanisms that regulate cytokinesis in normal cells and how this process may become mis-regulated in cancer
Blake Roessler: Role of Wnt, leptin, and IL6 signaling and mesenchymal stem cells in early osteoarthritis.
Jordan Shavit: We study the genetics of blood clotting disorders using zebrafish and mouse models.
Sivaraj Sivaramakrishnan: Molecular motors, FRET sensors, signal transduction in cardiomyocytes
Billy Tsai: Cellular entry mechanisms of toxins and viruses
Lois Weisman: Our overall goal is to uncover new, essential subcellular processes and to determine how defects in these pathways cause human diseases, such as cancer, diabetes and neurodegeneration.
Sunny Wong: Roles of hair follicle stem cells in tissue homeostasis, wound healing and cancer.
Bing Ye: Molecular and cellular mechanisms underlying neural circuit development in Drosophila

David Antonetti: Understanding retinal vascular dysfunction and macular edema in diabetic retinopathy and other blinding diseases.
Peter Arvan: Diseases caused by abnormal protein trafficking in the secretory pathway
Ernesto Bernal-Mizrachi: Regulation of beta cell mass and diabets
Tae-Hwa Chun: Role of MMP-dependent ECM remodeling in obesity and diabetes.
Thomas Gardner: We study the pathogenesis of diabetic retinopathy, particularly related to mechanisms of altered growth factor signaling, and in a translational research environment.
Gary Hammer: Dr. Hammer’s lab combines classic molecular biology techniques and whole animal models to study adrenocortical development and dyregulation that leads to adrenocortical carcinoma.
Jiandie Lin: Metabolic disease and mechanisms
Ming Liu: (pre)proinsulin misfolding, mistargeting, and diabetes
Malcolm J. Low: Our lab investigates the neuroendocrine regulation of appetite, feeding behavior, metabolism and stress using mutant mice, neuroanatomical tracing, pharmacology, and behavioral assays.
Peter Lucas: Mechanisms of NF-kB activation and their relevance to metabolic (particularly type II diabetes), vascular, and neoplastic diseases.
Vasantha Padmanabhan: Research focuses on developmental origin of reproductive and metabolic dysfunctions induced by inappropriate exposure to native and environmental steroids.
Ayyalusamy Ramamoorthy: Role of amylin misfolding, zinc and insulin on type II diabetes.
Alan Saltiel: Mechanisms of energy homeostasis.

Michael King: Behavioral and electrophysiological studies of vestibular and oculomotor systems in animals and human subjects.
Susan Shore: Multisensory process in the cochlear nucleus.

Kathleen Collins: Our long term goals are to understand viral mechanisms for establishing persistent infections
David Markovitz: We examine the interactions between retroviruses and human cells, and so have interests in AIDS, endogenous retroviruses, the DEK protein, cancer, and immunity
Akira Ono: We study virus-cell interactions with particular focus on cell biological aspects of HIV-1 assembly and spread.

Xing Fan: Brain cancer stem cells.
Thomas Glover: We are investigating the poorly understood molecular mechanisms involved in copy number variant (CNV) mutations in humans using both cell culture and mouse systems to explore genetic environmental factors
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Sundeep Kalantry: Epigenetics
Jeffrey Kidd: Understanding the biology of genomic variation.
Donna Martin: We study disorders of neural development and their relationship to human developmental disorders of the nervous system.
Miriam Meisler: We seek to identify genes responsible for neurological disease, including sodium channels, and to generate mouse models for understanding molecular mechanisms.
Diane Robins: We study basic mechanisms of gene regulation in androgen-dependent prostate cancer and in sexually dimorphic liver gene expression, using mouse and cell models.
JoAnn Sekiguchi: My lab studies the mechanisms underlying maintenance of genome stabilty and the impact of defects in these processes on disease outcomes, including immunodeficiency, lung disease and tumorigenesis.
Jordan Shavit: We study the genetics of blood clotting disorders using zebrafish and mouse models.
Cristen Willer: Find novel genes and genetic variants underlying cardiovascular disease using genome and exome sequencing and high-throughput genotyping arrays

Marilia Cascalho: Generation of diversity in health and disease
Maria Castro: Brain cancer biology, role of tumor ligands in hematopoietic stem cells' development, Toll receptor-mediated and STAT3 signaling; Development of novel therapeutic strategies.
Raymond Douglas: Investigation of autoimmune mechanisms of orbital disease
Irina Grigorova: Studying regulation of humoral (antibody) immune responses via standard immunological, intravital imaging and quantitative modeling approaches.
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Phil King: Genetic analysis of signal transduction inside and outside of the immune system
Gary Luker: Molecular imaging of receptor signaling pathways in primary and metastatic cancer
Yonqun Oliver He: Microbiology, immunology, and bioinformatics
Joseph Holoshitz: Innate and adaptive immune signaling in autoimmunity
Patrick Hu: We use C. elegans to study the molecular basis of aging and age-related disease
Mariana Kaplan: Mechanisms of autoimmunity and organ damage in lupus
David Markovitz: We examine the interactions between retroviruses and human cells, and so have interests in AIDS, endogenous retroviruses, the DEK protein, cancer, and immunity.
Beth Moore: Our laboratory studies exacerbation of lung fibrosis by gammaherpesviruses and also studies the reconstituion of innate and adaptive immunity following stem cell transplant
Gabriel Nunez: The laboratory is interested in signaling pathways regulating innate immunity, the pathogenesis of inflammatory disease and cancer.
Marc Peters-Golden: My lab studies the role and the cellular mechanisms by which important endogenous lipid mediators, particularly prostaglandins and leukotrienes, participate in inflammation, innate immunity, and lung fibrosis.
Blake Roessler: Role of Wnt, leptin, and IL6 signaling and mesenchymal stem cells in early osteoarthritis.
Michele Swanson: Legionella pneumophila, a genetic tool to analyze innate immunity and microbial differentiation
Vincent Young: Pathogens and the microbiome in human disease.

Vern Carruthers: Molecular pathogenesis of Toxoplasma gondii infections
Victor DiRita: Mechanisms of bacterial pathogenesis
Kathryn Eaton: Pathogenesis of Shigatoxigenic E. coli
Irina Grigorova: Studying regulation of humoral (antibody) immune responses via standard immunological, intravital imaging and quantitative modeling approaches.
Phil King: Genetic analysis of signal transduction inside and outside of the immune system
Gary Luker: Molecular imaging of receptor signaling pathways in primary and metastatic cancer
Yonqun Oliver He: Microbiology, immunology, and bioinformatics
Akira Ono: We study virus-cell interactions with particular focus on cell biological aspects of HIV-1 assembly and spread.
Cheong-Hee Chang: We study molecular mechanisms by which innate CD4 T cells develop and function.
Yasmina Laouar: Regulation of innate immune responses
Mark Saper: Structural and biochemical studies to understand how a newly identified lipoprotein regulates peptidoglycan synthesis in pathogenic bacteria.
Michele Swanson: Legionella pneumophila, a genetic tool to analyze innate immunity and microbial differentiation
Vincent Young: Pathogens and the microbiome in human disease.

Yali Dou: Epigenetic regulation in embryonic stem cells and cancer stem cells.
Greg Dressler: We use biochemical and genetic models to study how stem cells make adult tissues and organs.
Xing Fan: Brain cancer stem cells.
Elizabeth Lawlor: Cancer and stem cell biology
Sem Phan: Molecular and cellular mechanisms of lung injury, inflammation and fibrosis.
Peter Lucas: Mechanisms of NF-kB activation and their relevance to metabolic (particularly type II diabetes), vascular, and neoplastic diseases.
Gabriel Nunez: The laboratory is interested in signaling pathways regulating innate immunity, the pathogenesis of inflammatory disease and cancer.
Jean-Francois Rual: Characterization of the notch molecular network in glioblastoma and medulloblastoma
Thomas Wilson: The Wilson laboratory studies structural genome (in)stability and its relationship to double-strand break repair (dys)function using experimental manipulation of DNA repair proteins and global genomic/bioinformatic approaches.

Jimo Borjigin: Mechanisms of circadian timing and injury-induced neuroplasticity
Christin Carter-Su: We study signal transduction pathways involving tyrosine kinases with special emphasis on JAK/Stat signaling pathways and the adapter protein SH2B1 in the context of human obesity, cell motility, and neuronal development.
Dan Goldman: Retina, optic nerve and motor neuron regeneration
Ao-Lin Hsu: We study genes involved in the regulation of longevity and aging.
Lori Isom: Molecular basis of inherited epilepsy and cardiac arrhythmia caused by sodium channel mutations.
Jose Jalife: Our work focuses on the understanding of the fundamental mechanisms of complex, life-threatening arrhythmias and sudden cardiac death
Michael Lehman: Neural circuitry controlling reproduction.
Malcolm J. Low: Our lab investigates the neuroendocrine regulation of appetite, feeding behavior, metabolism and stress using mutant mice, neuroanatomical tracing, pharmacology, and behavioral assays.
Carey Lumeng: How inflammatory cells modify metabolism associated with obesity-related diseases.
Juanita Merchant: My lab focuses on the role of chronic inflammation in the GI tract as a trigger for gastric or colon cancer.
Geoffrey Murphy: How voltage-gated ion channels regulate neuronal function and complex behaviors
Vasantha Padmanabhan: Research focuses on developmental origin of reproductive and metabolic dysfunctions induced by inappropriate exposure to native and environmental steroids.
Alan Saltiel: Mechanisms of energy homeostasis.
Linda Samuelson: Notch pathway regulation of gastrointestinal stem/progenitor cell proliferation and differentiation.
Santiago Schnell: In the Schnell Lab, we are interested in investigating cellular physiology systems comprising many interacting components, where computational modelling and theory may aid in the identification of the key mechanisms underlying the behaviour of the system as a whole.
Yatrik Shah: Understanding the role of oxygen sensing in gastrointestinal diseases
Michael Sutton: Molecular mechanisms controlling synapse development and plasticity
Hector Valdivia: Cardiac Arrhythmias

David Antonetti: Understanding retinal vascular dysfunction and macular edema in diabetic retinopathy and other blinding diseases.
Philip Gage: Cell signaling pathways and transcriptional networks regulating eye development and disease
Thomas Gardner: We study the pathogenesis of diabetic retinopathy, particularly related to mechanisms of altered growth factor signaling, and in a translational research environment.
Peter Hitchcock: We study developmental and regenerative neurogenesis in the vertebrate retina
Bret Hughes: My lab seeks to understand the rol of ion channels in the retinal pigment epithelium in health and diesase using electrophysiological, imaging, and molecular biology approaches.
Alon Kahana: Neural crest development and craniofacial tissue regeneration.
Donald Puro: Retinovascular physiology and pathobiology with a focus on the role of ion channels and the effects of diabetes
Terry Smith: Molecular pathogenesis of autoimmunity focusing on Graves disease as a model for tissue inflammation and remodeling
Hisashi Umemori: Wiring the functional brain: specific synapse formation and activity-dependent synapse refinement
Kwoon Wong: Electrophysiology of the retina
David Zacks: Our laboratory investigates the molecular mechanisms controlling photoreceptor survival during retinal disease..

Cynthia Tsui: Kidney degeneration and regeneration pathways at the blood-urine interface that result in chronic kidney disease.

Huda Akil: Neurobiology of Emotions
Xing Fan: Brain cancer stem cells.
Eva Feldman: Our laboratory focuses on understanding the pathogenic mechanisms that trigger neurodegeneration, specifically during diabetes, amyotrophic lateral sclerosis and Alzheimer's disease, and identifying effective therapies using a multifaceted approach consisting of active programs in basic, translational and clinical research.
John Fink: Molecular basis of inherited brain and spinal cord disorders
Donna Martin: We study disorders of neural development and their relationship to human developmental disorders of the nervous system.
Jack Parent: We study neural stem cell biology and its role in brain repair and neurological disease.
Vikram Shakkottai: Physiologic changes in ataxia
Robert Thompson: microRNA Actions in the CNS
Peter Todd: We study the roles of RNA and RNA processingin neurodegenerative disease.

Huda Akil: Neurobiology of Emotions
J. Wayne Aldridge: We to elucidate individual differences in basal ganglia neural coding of food and drug cues in rats for which the cue is both a predictor and an incentive stimulus for behavioral action.
David Antonetti: Understanding retinal vascular dysfunction and macular edema in diabetic retinopathy and other blinding diseases.
Jimo Borjigin: Mechanisms of circadian timing and injury-induced neuroplasticity
Maria Castro: Brain cancer biology, role of tumor ligands in hematopoietic stem cells' development, Toll receptor-mediated and STAT3 signaling; Development of novel therapeutic strategies.
Xing Fan: Brain cancer stem cells.
Eva Feldman: Our laboratory focuses on understanding the pathogenic mechanisms that trigger neurodegeneration, specifically during diabetes, amyotrophic lateral sclerosis and Alzheimer's disease, and identifying effective therapies using a multifaceted approach consisting of active programs in basic, translational and clinical research.
Daniel Ferris: Biomechanics and neural control of human locomotion.
John Fink: Molecular basis of inherited brain and spinal cord disorders

Peter Hitchcock: We study developmental and regenerative neurogenesis in the vertebrate retina
Michael King: Behavioral and electrophysiological studies of vestibular and oculomotor systems in animals and human subjects.
Michael Lehman: Neural circuitry controlling reproduction.
Pedro Lowenstein: We study the cellular, molecular and mathematical basis of cancer; stem cells, nanoparticles, and gene therapy are used in experimental models, and in early clinical trials in patients.
Miriam Meisler: We seek to identify genes responsible for neurological disease, including sodium channels, and to generate mouse models for understanding molecular mechanisms.
Geoffrey Murphy: How voltage-gated ion channels regulate neuronal function and complex behaviors
Jack Parent: We study neural stem cell biology and its role in brain repair and neurological disease.
Donald Puro: Retinovascular physiology and pathobiology with a focus on the role of ion channels and the effects of diabetes
Gabrielle Rudenko: Our laboratory studies proteins involved in synapse formation, maturation and maintenance.
Rachael Seidler: Cognitive neuroscience of motor behavior
Susan Shore: Multisensory process in the cochlear nucleus.
Michael Sutton: Molecular mechanisms controlling synapse development and plasticity
Robert Thompson: microRNA Actions in the CNS
Peter Todd: We study the roles of RNA and RNA processingin neurodegenerative disease.
John Traynor: Biology of Drug Abuse
Kwoon Wong: Electrophysiology of the retina
Bing Ye: Molecular and cellular mechanisms underlying neural circuit development in Drosophila
David Zacks: NIH-funded lab studying photoreceptor degeneration in a variety of disease processes.
Jon-Kar Zubieta: Neuroimaging research in mechanisms related to substance abuse risk during development and genetic modulators.

Dean Brenner: Biomarkers for GI Cancer Early Detection
Margaret Gnegy: Role of protein kinase C in amphetamine-stimulated dopamine efflux and behavior
Ronald Holz: Biophysics of exocytosis
Lori Isom: Molecular basis of inherited epilepsy and cardiac arrhythmia caused by sodium channel mutations.
Benedict Lucchesi: Integrative cardiovascular research.
Yoichi Osawa: Control of Nitric Oxide Synthase by Drugs and Chaperones
Gabrielle Rudenko: Our laboratory studies proteins involved in synapse formation, maturation and maintenance.
John Traynor: Biology of Drug Abuse

Ron Buckanovich: Study of cancer stem cells and the tumor vascular niche
Yali Dou: Epigenetic regulation in embryonic stem cells and cancer stem cells.
Greg Dressler: We use biochemical and genetic models to study how stem cells make adult tissues and organs.
Xing Fan: Brain cancer stem cells.
Eva Feldman: Our laboratory focuses on understanding the pathogenic mechanisms that trigger neurodegeneration, specifically during diabetes, amyotrophic lateral sclerosis and Alzheimer's disease, and identifying effective therapies using a multifaceted approach consisting of active programs in basic, translational and clinical research.
Jun-Lin Guan: We are interested in the role of tyrosine kinase signaling in breast cancer stem cells, tumor angiogenesis and metastasis as well as autophagy in breast cancer and other disease processes.
Gary Hammer: Dr. Hammer’s lab combines classic molecular biology techniques and whole animal models to study adrenocortical development and dyregulation that leads to adrenocortical carcinoma.
Tom Kerppola: Roles of protein interactions and nucleoprotein complexes in development and disease
Pedro Lowenstein: We study the cellular, molecular and mathematical basis of cancer; stem cells, nanoparticles, and gene therapy are used in experimental models, and in early clinical trials in patients.
Beth Moore: Our laboratory studies exacerbation of lung fibrosis by gammaherpesviruses and also studies the reconstituion of innate and adaptive immunity following stem cell transplant
Blake Roessler: Role of Wnt, leptin, and IL6 signaling and mesenchymal stem cells in early osteoarthritis.
Linda Samuelson: Notch pathway regulation of gastrointestinal stem/progenitor cell proliferation and differentiation.
Sunny Wong: Roles of hair follicle stem cells in tissue homeostasis, wound healing and cancer.

Gabrielle Rudenko: Our laboratory studies proteins involved in synapse formation, maturation and maintenance.

University of Michigan Medical School

Participating Faculty