University of Michigan Center for Gastrointestinal Research


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    2017 - 2018

    UMCGR Weekly Noon Conference

    1/11/16-Jeffery Perry, Ph.D. "Functional mapping of the Dengue virus genome by insertional mutagenesis and next generation sequencing"

    1/18/16-Andrew Shreiner, M.D. "Description of a clinical study on the impact of dietary FODMAPs on functional GI symptoms in Crohn's patients"

    1/25/16-John Kao, M.D. "Presenting National Meetings"

    2/1/16-Mo El-Zaatari, Ph.D. "Novel mechanisms mediating GI pre-neoplasia"

    2/8/16-Bishr Omary, M.D., Ph.D. "When is it time to tell your story & to which journal"

    02/15/16-Kate Walton, Ph.D. "Building Intestinal Villi"

    3/7/16-Melody Zeng, Ph.D. "Research Update"

    3/14/16-Rebecca Hughes, Ph.D. and Joe Austin, Ph.D. "IRB 101 Discussion"

    3/21/16-Chung Owyang, M.D. "Academic Skills Workshop Seminar titled "How to write a successful R01 Grant"

    3/28/16-Jason Spence, Ph.D. "Research Advice"

    4/11/16-Alana Chin, Ph.D. "β-catenin destruction complex-independent regulation of hippo-YAP signaling by APC in Intestinal Tumorigenesis"

    4/18/16-Andrea Wright, Ph.D. "Body Composition in Non-Alcoholic Fatty Liver Disease: An Analysis of the Framingham Heart Study"

    4/25/16-Daniel Triner, Ph.D. "Pro-Inflammatory HIF-2a/MAZ Signaling in Colitis and Colon Cancer"

    5/2/16-Graham Brady, M.D. "Role of nuclear lamins in liver disease"

    5/9/16-Heather Schofield, Ph.D. "Elucidating the Role of Bmi1 in Pancreatitis and the Initiation of Pancreatic Cancer"

    5/16/16-Kate Walton, Ph.D. "Defining the role of vasculature in villus morphogenesis"

    No weekly noon seminars for summer months June, July and August

    9/19/16-Heather Schofield, Ph.D. and Daniel Triner, Ph.D., (Research Updates) "New mouse model demonstrates the necessity of mutant p53 expression for pancreatic cancer progression" and "MAZ as a novel regulator of the proinflammatory response in colitis and colon cancer"

    9/26/16-Graham Brady, M.D., and Joseph Pickard Ph.D., (Research Updates) "Role of nuclear lamina in liver disease" and "Mechanisms of colonization resistance to enteric pathogens"

    10/3/16-Tina Morhardt, M.D., and Holly Turala, Ph.D., "IL-10 producing small intestinal macrophages has protective role in intestinal inflammation" and "Host and bacterial modulation of norovirus pathogenesis"

    10/10/16-Matthew Sturm, M.D. "Multiplexed molecular imaging of biliary intraepithelial neoplasia; imaging strategies for the early detection of cancer in indeterminate biliary strictures"

    10/17/16-Marina Pasca di Magliano, Ph.D., "Myeloid cells regulate Acinar cell plasticity and pancreatic remodeling in mice".

    10/24/16-Heather Schofield, Ph.D. "Journal Club"

    10/31/16-Jeffery Perry, Ph.D., "Investigation of Dengue Virus through Functional Mapping of Its Genome"

    11/7/16-Christiane Wobus, Ph.D., "Mechanisms of Norovirus - host Interactions"

    11/14/16-Daniel Triner, Ph.D., "IRAK-M expression in tumor cells supports colorectal cancer progression through reduction of antimicrobial defense and stabilization of STAT3"

    11/21/16-Eric Martens, Ph.D., "Degradation of Complex Carbohydrates By Human Gut Bacteria During Health & Disease"

    11/28/16-Graham Brady, M.D., "p62/SQSTM1 by binding to vitamin d receptor inhibits hepatic stellate cell activity, fibrosis, and liver cancer"

    12/05/16-Juanita L. Merchant, M.D., Ph.D., “Men1 Gastrinomas”

    12/12/16-Yatrik Shah, Ph.D., "Intestinal Control of Systemic Iron Homeostasis"

    12/19/16-Linda Samuelson, Ph.D., "Dynamic regulation of intestinal stem cell self-renewal by notch signaling"

    12/26/16- No Conference

    01/30/17- Nobuhiko Kamada, Ph.D., "The Gut Microbiota and IBD"

    02/06/17- Joseph Pickard, Research, “Stable Engraftment of Bifidobacterium longum AH1206 in the Human Gut Depends on Individualized Features of the Resident Microbiome”

    02/13/17-Bishr Omary, M.D., Ph.D., Professor & Chair, Molecular & Integrative Physiology, and Professor of Internal Medicine, "Physiologic Exosomal Release of a Mitochondrial Enzyme Into Bile and Its Function As Circulatory Cytokine During Liver Injury"

    02/20/17- Matthew Sturm, M.D., GI Fellow, "A Tissue Systems Pathology Test Detects Abnormalities Associated with Prevalent High-Grade Dysplasia and Esophageal Cancer in Barrett's Esophagus"

    02/27/17- No Conference

    03/06/17- Elise Demitrack, Ph.D., "Wnt and Notch Regulation of Human Gastric Stem Cells"

    03/13/17- Thomas Wang, M.D., Ph.D., "Opportunities for Molecular Imaging in the Digestive Tract"

    03/20/17- Heather Schofield, Graduate Student,  "A New Mouse Model Demonstrates the Necessity of Mutant p53 Expression for Pancreatic Cancer Progression"

    03/27/17- Daniel Triner, student in the M.D./Ph.D., "Opposing Roles of Intratumoral Neutrophils in Colon Cancer"

    04/03/17-No Conference

    04/10/17- Canceled: Graham Brady, M.D., GI Fellow, "Role of the Nuclear Lamina in Nonalcoholic Fatty Liver Disease"

    04/10/17- Dhiman Maitra, Ph.D., Post-Doctoral Fellow from the Bishr Omary Lab, "A Novel Mechanism of Porphyria-Associated Cellular Toxicity"

    04/17/17 Gabriel Núñez, M.D., Paul de Kruif Professor of Pathology, "Control of Pathogen Colonization by Host Immunity and the Microbiota"

    04/24/17- Holly Turula, Graduate Student, "Secretory Immunoglobulins Enhance Norovirus Infection by Promoting Immune Tolerance"

    05/01/17- Tina Morhardt, M.D., "The Role of IL-10-producing Resident Macrophages in Small Intestinal Homeostasis”

    05/08/17-  DDW – No Conference

    05/15/17-  Joseph Pickard, Research, "Canceled"                                                                                       
    05/22/17- Matthew Sturm, M.D., GI Fellow, "Molecular Imaging Strategies for Dysplasia and Early Cancer Detection in Barrett's Esophagus"                                                                                              
    05/29/17- Memorial Day

    06/05/17- Joseph Pickard, Research Fellow, "Identifying Molecular Mechanisms of Colonization Resistance to Enteric Pathogens”

    06/12/17- Graham Brady, M.D., GI Fellow, "Nuclear Lamina-Related Variants in a Cohort of Twins with NAFLD”

    2017 Visiting Professor Seminars

    The UMCGR Visiting Professor Seminar Series has been temporarily suspended as the Center grant is on no-cost time extension currently.


    2017 Annual Academic Workshop and Retreat

    Friday February 03, 2017

    Presentations by T32 Trainees and Pilot Awardees in the Medical Science Research Building room 6530.
    Presenters: Daniel Triner, Heather Schofield, Tina Morhardt, M.D., Graham Brady, M.D., Ph.D., Joseph Pickard, Ph.D., Matthew Sturm, M.D., Holly Turula, Nataliya Razumilava, M.D., and P. Kay Lund, Ph.D.

    12:30 – 12:40 PM- Welcome by Chung Owyang, M.D/John Kao, M.D.
    12:40 – 1:10 PM- Daniel Triner, Medical Scientist Training Program, Molecular and Integrative Physiology, University of Michigan Medical School. "HIF-2α/MAZ signaling in intestinal inflammation and colon cancer"                                            
    1:10 – 1:40 PM- Heather Schofield, Graduate Student Instructor, Cell and Developmental Biology, Medical School. "A New Mouse Model Demonstrates the Necessity of Mutant p53 Expression for Pancreatic Cancer Progression"

     1:40 – 2:10 PM-Tina Morhardt, M.D., M.S., House Officer, Pediatrics Gastroenterology, University of Michigan Hospitals.  "Role of resident macrophages in the small intestinal homeostasis"

     2:10 – 2:40 PM- Graham Brady, M.D., Ph.D., House Officer, Division of Gastroenterology, Internal Medicine. "Role of the nuclear lamina in liver disease"

    2:40 – 2:50 PM Break

    2:50 – 3:20 PM- Joseph Pickard, Ph.D., Research Fellow, Pathology, Medical School.  "Identifying molecular mechanisms of colonization resistance to enteric pathogens"

     3:20 – 3:50 PM- Matthew Sturm, M.D., House Officer, Internal Medicine Gastroenterology, University of Michigan Hospitals.   "Biomarkers of Biliary Intraepithelial Neoplasia; Imaging strategies for the early detection of cholangiocarcinoma in indeterminate biliary strictures"

     3:50 – 4:20 PM- Holly Turula, Graduate Student Instructor and Graduate Student Research Assistant, Microbiology and Immunology, Medical School. "Host Modulation of Norovirus Pathogenesis"

     4:20 – 4:50 PM- Nataliya Razumilava, M.D., Clinical Lecturer, Division of Gastroenterology, Internal Medicine, University of Michigan Hospitals. "The role of Hh signaling in maintenance of biliary tract homeostasis"

     4:50 – 5:00 PM- Break  

     5:00 – 6:00 PM- Presentation by P. Kay Lund, Ph.D., Director, Division of Biomedical Research Workforce, NIH Extramural Research Training Officer, Office of Extramural Research (OER), Office of the Director (OD), National Institutes of Health (NIH), as our key note speaker and fifth year Yamada Lectureship honoree. "From Bench Research and Mentoring to the NIH: the journey, the rewards and lessons learned"

    Saturday, February 04, 2017 (Retreat Keynote Speaker)

    P. Kay Lund, Ph.D., Director, Division of Biomedical Research Workforce, NIH Extramural Research Training Officer, Office of Extramural Research (OER), Office of the Director (OD), National Institutes of Health (NIH), as our key note speaker and fifth year Yamada Lectureship honoree. Topic: Intestinal stem cells in health and disease: Regulation by hormones, nutrients and microbes. 10:15-11:15 AM, Michigan League, Hussey Room on the second floor. Hosted by The Michigan Center for Gastrointestinal Research.


    2017 Midwest DDRCC Academic Workshop- Cincinnati Children's Hospital Heath Center February 27-28th

    Monday February 27th

    Morning Session


    Afternoon Session


    Evening Session


    Tuesday February 28th



* Co-sponsored seminars


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