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Dr. Carol Chenoweth

Description of Research: Carol Chenoweth

Our research centers around the epidemiology of healthcare associated infections and antibiotic resistant organisms:

Healthcare-associated infections
The major focus of our research has been the epidemiology and prevention of hospital associated infections in high risk patient populations. Our analysis of candidemia in a children’s hospital identified that hyperalimentation was an independent risk factor for candidemia in children. In a similar type of study, mucositis was identified as the key risk factor for the development of anaerobic bacteremia in bone marrow transplant recipients. Two cohort studies have highlighted the prevalence of nosocomial infections in patients undergoing high risk procedures, such as extracorporeal membrane oxygenation or left ventricular assist devices. We have two current studies near completion on healthcare-associated infections in the home setting.

Emerging antibiotic resistance
We have an interest in antibiotic resistant organisms in community and hospital pathogens, especially antibiotic resistant enterococci. A study of vancomycin-resistant enterococcus colonization in patients awaiting liver transplantation is in final stages of manuscript preparation. In addition, we are participating in a multicenter study to evaluate efficacy of control measures for prevention of spread of vancomycin-resistant enterococci and methicillin-resistant staphylococci in the ICU setting.

Recent Publications

Chenoweth CE, Bassin BS, Hartley SE, Mack MR, Kunapali A, Park P, Quint DJ, Seagull FJ, Wesorick DH. Vertebral osteomyelitis, discitis and spinal epidural abscess in adults. Office of Clinical Affairs, University of Michigan Health System, 2013. [Available from the Agency for Healthcare Research and Quality at www.guideline.gov] [practice guideline].

Baxi SM, Shuman EK, Scipione CA, Chen B, Sharma A, Rasanathan JJ, Chenoweth CE. Impact of postplacement adjustment of peripherally inserted central catheters on the risk of bloodstream infection and venous thrombus formation: a cohort study. Infect Control Hosp Epidemiol 2013; 34(8):785-92. PMID:238382

Thomas JG, Chenoweth CE, Sullivan SE. Iatrogenic Creutzfeldt-Jakob via surgical instruments: challenges in neurosurgery. J Clin Neurosci 2013; 34(8): 1207-12. PMID: 23896549

Hartley S, Valley S, Kuhn L, Washer LL, Gandhi T, Meddings J, Chenoweth C, Malani AN, Saint S, Srinivasan A, Flanders SA. Inappropriate testing for urinary tract infection in hospitalized patients: an opportunity for improvement. Infect Control Hosp Epidemiol 2013; 34(11): 1204-7. PMID 24113606

Talsma A, Galecki A, Chenoweth CE, Geun HG, Campbell D. Baseline measure of alcohol-based skin preparation agents prior to 2011 NQF recommendation in general surgery population. Infect Control Hosp Epidemiol 2013;34(11):1211-4. PMID 24113608

Rosenthal M, Aiello A, Larson E, Chenoweth C, Foxman B. Healthcare workers’ hand microbiome may mediate carriage of hospital pathogens. Pathogens MDPI 2014;3(1):1-13.

Chenoweth CE, Gould CV, Saint S. Diagnosis, Management, and prevention of catheter-associated urinary tract infections. Infect Dis Clin N Am 2014;28(1):105-119.PMID 24484578

Chopra V, Ratz D, Kuhn L, Lopus T, Chenoweth C, Krein S. Peripherally inserted central catheter-associated bloodstream infections: prevalence, patterns, and predictors. Am J Med 2014; epub ahead of print. PMID 24440542

Rosenthal M, Aiello AE, Chenoweth C, Goldberg D, Larson E, Gloor G, Foxman B. Impact of technical sources of variation on the hand microbiome dynamics of healthcare workers. Plos One 2014;9(2):e88999. PMID:24551205

Hammoud M, Kraft C, Pulst-Korenberg J, Chenoweth C, Gregg KS. Disseminated Nocardia paucivorans infection in an immunocompetent host. Infection 2014; epub ahead of print PMID:24634088


 
   
   

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