Research Faculty

Jon Oscherwitz, M.D.
Associate Research Scientist
Phone: 734-845-5195

Campus address:
University of Michigan
VAMC, Research Service 151
2215 Fuller Road/SPC 2399
Ann Arbor, MI 48105

Research Interests

Molecularly targeted vaccines for Bacillus anthracis and Staphylococcus aureus
Alzheimer's Disease vaccine therapeutics
Cancer immunotherapeutics and vaccines

Education and Training

1984 B.A., DePaul University, Chicago, IL
1991 M.D., University of Chicago, Pritzker School of Medicine
1992-1993 Postdoc training, University of Michigan Comprehensive Cancer Center, Dr. Paula Bockenstedt
1993-1996 Research Fellow, University of Michigan Comprehensive Cancer Center, Dr. Kemp Cease

Honors & Awards

1995 Trainee Investigator Award, CSCR Annual meeting
2010-2011 University of Michigan UROP, Outstanding Research Mentor Award

Memberships in Professional Societies

  American Society for Microbiology
  American Association for the Advancement of Science
  American Association of Immunologists
  International Society for Vaccines

Editorial Positions, Boards, and Peer-Review Service

  Ad hoc Reviewer, Journal of Immunology
  Ad hoc Reviewer, Infection and Immunity
  Ad hoc Reviewer, Vaccine
  Ad hoc Reviewer, Clinical Vaccine Immunology
  Ad hoc Reviewer, Microbiology and Immunology

Selected Publications (2008-present)

Liu TH, Oscherwitz J, Schnepp B, Jacobs J, Yu F, Cease KB, Johnson PR.  Genetic vaccines for anthrax based on recombinant adeno-associated virus vectors. Mol Ther, 2009 Feb; 17(2):373-379. (PMID 19002162)  PMC 2835057.

Oscherwitz J, Yu F, Jacobs JL, Liu TH, Johnson PR, Cease KB.  Synthetic peptide vaccine targeting a cryptic neutralizing epitope in domain 2 of Bacillus anthracis protective antigen. Infect Immun, 2009 Aug; 77(8):3380-3388. (PMID 19487468)  PMC 2715696.

Oscherwitz J, Yu F, Cease KB.  A heterologous helper T-cell epitope enhances the immunogenicity of a multiple-antigenic-peptide vaccine targeting the cryptic loop-neutralizing determinant of Bacillus anthracis protective antigen. Infect Immun, 2009 Dec; 77(12):5509-5518. (PMID 19805525)  PMC 2786483.

Oscherwitz J, Gribbin TE, Cease KB.  A CD20 tandem-epitope immunogen elicits antibody in mice that binds murine cell surface CD20 and depletes splenic B cells in vivo. Mol Immunol, 2010 Apr; 47(7-8):1484-1491. (PMID 20189250).

Ingram RJ, Chu KK, Metan G, Maillere B, Doganay M, Ozkul Y, Dyson H, Williamson ED, Baillie L, Kim LU, Ascough S, Sriskandan S, Altmann DM, Oscherwitz J, Cease K.  An epitope of Bacillus anthracis protective antigen that is cryptic in rabbits may be immunodominant in humans. Infect Immun, 2010 May; 78(5):2353; author reply 2353-2354. (PMID20400683)  PMC 2863510.

Oscherwitz J, Yu F, Cease KB.  A synthetic peptide vaccine directed against the 2ss2-2ss3 loop of domain 2 of protective antigen protects rabbits from inhalation anthrax. J Immunol, 2010 Sep 15; 185(6):3661-3668. (PMID 20696862).

Oscherwitz J, Yu F, Jacobs JL, Cease KB.  Recombinant vaccine displaying the loop-neutralizing determinant from protective antigen completely protects rabbits from experimental inhalation anthrax. Clin Vaccine Immunol, 2013 Mar; 20(3):341-349. (PMID 23283638) PMC 3592347.

Rev. 7/16