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PROGRAM SCHEDULE

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BSRB at Univ of Mich

Wednesday, May 22, 2013

ATRIUM/SEMINAR ROOMS ABC
12:00–2:00 pm

Arrivals, Check-in, Poster Set-up, and Lunch

(Posters will be located in the outer entrance lobby)

AUDITORIUM
2:00–2:15 pm Welcome and Introduction (PETER ARVAN and LESLIE SATIN)

2:15–3:30 pm SESSION 1: ISLET DEVELOPMENT & EARLY GROWTH
(Moderator: Maureen Gannon)

2:15–2:30 pm TERESA MASTRACCI – “Regulation of Neurod1 contributes to the lineage potential of neurogenin3+ endocrine precursor cells in the pancreas”
2:30–2:45 pm FONG CHENG PAN – “Mnx1 as a critical determinant in beta- versus delta-cell fate during endocrine lineage diversification”
2:45–3:00 pm LIHUA YE – “Glucagon is a critical regulator of beta cell neogenesis in zebrafish”
3:00–3:15 pm EMILYN ALEJANDRO – “mTOR signaling contributes to developmental programming of the pancreatic beta-cell”
3:15–3:30 pm ELIZABETH CONRAD – “The role of MafB in the maturation and maintenance of islet beta-cells”

SEMINAR ROOMS ABC
3:30-4:00 pm Coffee/Tea Break

AUDITORIUM
4:00–5:15 pm SESSION 2: ADULT ISLET BETA CELL GROWTH & REGENERATION (Moderator: Ryan Anderson)

4:00–4:15 pm DANIELLE DEAN – “Search for a circulating hepatic factor that promotes alpha cell proliferation”
4:15–4:30 pm XIANGWEI XIAO – “No evidence for beta cell neogenesis in the adult pancreas”
4:30–4:45 pm MARIA GOLSON – “Activated FoxM1 enhances recovery after beta cell ablation”
4:45–5:00 pm JUSTIN BUSHKOFSKY – “Tcf19 is a novel islet factor important in cell survival and proliferation”
5:00–5:15 pm MANUEL BLANDINO-ROSANO – “Deletion of 4E-BP2 induces beta cell proliferation and mass and confers resistance to streptozotocin induced diabetes”

5:15–6:00 pm Break

ATRIUM
6:00–7:30 pm Dinner

LOBBY (near outer entrance, opposite elevators)
7:30–10:00 pm POSTER SESSION (64 posters)

CLICK HERE TO VIEW THE POSTER PRESENTATIONS!

 

 

Thursday, May 23, 2013

SEMINAR ROOMS ABC
8:00–9:15 am Breakfast

AUDITORIUM
9:15–10:30 am SESSION 3: THE INSULIN FACTORY — A VISIT TO THE PRODUCTION LINE & WAREHOUSE (Moderator: Fumihiko Urano)

9:15–9:30 am ANDREW TEMPLIN – “Proinflammatory cytokines induce an ER stress response that activates an alternative mRNA translational program”
9:30–9:45 am HUAN GUO – “Inefficient preproinsulin translocation links to late onset diabetes”
9:45–10:00 am ANGELA LOMBARDI – “Interferon-alpha as a trigger for autoimmunity in type 1 diabetes: the critical role of endoplasmic reticulum stress”
10:00–10:15 am MELKAM KEBEDE – "Diabetes-associated SORCS1 gene regulates islet insulin content and fasting glycemia under metabolic stress”
10:15–10:30 am VICTOR CAZARES – “Specific actions of Rab3 and Rab27 on late stages of Ca2+-regulated exocytosis of insulin”

SEMINAR ROOMS ABC
10:30–11:00 am Coffee/Tea Break

AUDITORIUM

11:00 am–12:15 pm SESSION 4: ISLET CELL REGULATION — NOVEL & NEGLECTED PATHWAYS (Moderator: David Jacobson)

BSRB interior view

11:00–11:15 am JIM REN – “Slow electrical oscillations in pancreatic beta cells from mice lacking KATP channels”
11:15–11:30 am MUFADDAL SONI – “MiRNAs 132 and 212 result in a down-regulation of CACT, leading to an increase in insulin secretion via fatty acyl-carnitine accumulation”
11:30–11:45 am STEPHANIE VILLA – “Investigation of a short chain fatty acid receptor, FFAR2, in the regulation of insulin secretion and beta cell mass”
11:45 am–12:00 pm MARK PERELIS – “Interplay between genotype, temporal phase, and age in circadian induced diabetes mellitus and beta-cell failure”
12:00–12:15 pm WILFREDO ROSARIO – “A functionally-relevant map of the brain’s direct linkage to pancreatic islets”

SEMINAR ROOMS ABC
12:30–2:00 pm Lunch

AUDITORIUM
2:00–3:15 pm SESSION 5: DYSFUNCTION & DESTRUCTION OF ISLET ß-CELLS (Moderator: Nathalie Fiaschi-Taesch)

2:00–2:15 pm DECHENG REN – “Bim and Puma mediate beta cell death in Pdx1 deficiency”
2:15–2:30 pm PAIGE COOPER – “Role of altered glucose metabolism in the glucotoxic progression of KATP induced neonatal diabetes1”
2:30–2:45 pm ANGELA HENSCHEL – “Biobreeding (BB) rat islets exhibit underlying islet dysfunction independent of insulitis and T1D onset”
2:45–3:00 pm ZACHARY R. SHAHEEN – “Investigating mechanisms of macrophage inflammatory and survival responses to EMCV, a diabetogenic virus”
3:00–3:15 pm AARTHI MAGANTI – “The lysine methyltransferase Set7/9 is a Pdx1-interacting cofactor that is required for normal islet function”

SEMINAR ROOMS ABC
3:15–3:45 pm Coffee/Tea Break

AUDITORIUM
3:45–5:00 pm SESSION 6: PREDICTING & FIXING DIABETES
(Moderator: Franck Mauvais-Jarvis)

3:45–4:00 pm MICHAEL MORRAN – “Non-synonymous single nucleotide polymorphisms (SNPs) in the IA-2 gene improve prediction of type 1 diabetes”
4:00–4:15 pm JOSHUA NEUMAN – “Delineating the signaling mechanisms downstream of the EP3 receptor and G{alpha}z protein in beta-cells”.
4:15–4:30 pm YIPING MAO – “Role of microRNA-30d in activating MafA in pancreatic beta cells”
4:30–4:45 pm CARLY KIBBE – “Cholecystokinin protects pancreatic beta cells from stress-induced apoptosis”
4:45–5:00 pm RAYMOND PASEK – “Connective tissue growth factor promotes glucose clearance during pregnancy”

SEMINAR ROOMS ABC
5:00–5:30 pm Coffee/Tea Break

 

gerold grodskyAUDITORIUM
5:45–7:00 pm SESSION 7: 6th ANNUAL LACY MEDAL LECTURE
(Moderator: CHRISTOPHER RHODES)

Gerold M. Grodsky, Ph.D. (UCSF)
“Insulin-Secretion Kinetics: A Historical Look into the Future”

 

ATRIUM
7:00-10:00 pm Awards Banquet, Entertainment, and Poster Mingling

 

Friday, May 24, 2013

Departures