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Pilot and Exploratory Studies Core (PESC)

The goal of the Pilot and Exploratory Studies Core is to provide support for studies that will develop and test new research ideas of high relevance to the Center's overall theme, the predictors and modulators of the aging phenotype and the ways in which genetic, environmental, and social factors influence late life disease through effects on the aging process.  The PESC will thus fund pilot research studies over a wide range of disciplines, ranging from basic genetics and physiology through behavioral and health services research.  Four current projects include studies of: (a) the genetics of bone chemistry and fragility; (b) a new system for investigation of insulin sensitivity using muscle explants; (c) factors modifying risk of falls in frail and healthy elderly subjects; and (d) the influences of gender and ethnic group on trajectories of alcohol consumption.

Core Director: Lona Mody, M.B.B.S., M.Sc.