22 Research and Innovation Impact Impact Through Partnerships Diverse, multidisciplinary, and global partnerships amplify the impact of our research mission. Inter-institutional Collaboration In a unique partnership that leverages the strengths of all parties, the University of Michigan Center for Integrative Research in Critical Care (MCIRCC) partners with the U.S. Department of Defense (DoD) and The Massey Foundation to fund new research that impacts the way severe traumatic brain injury (TBI) is diagnosed and treated. TBI is the fourth leading cause of death in the U.S. with 52,000 deaths per year. The partners work together to host The Massey Foun- dation TBI Grand Challenge, which invites researchers to engage and partner in groundbreaking research in severe TBI and to submit project proposals for funding. Funding is awarded to teams developing diagnostic, device, therapeutic or health information technology solutions that address the initial “golden hour” and critical 24 to 48 hours of care following a severe TBI. The 12-month projects are reviewed by researchers, physicians, and scientists from U-M and neurotrauma leadership from the DoD. The Massey Foundation funding comes from a gen- erous gift from the Joyce and Don Massey Family, in honor of Joyce, who sustained a life-altering TBI from an automobile crash. The DoD offers expertise and resources to support this project, and has a particular interest in the topic, as service members and their families represent the largest US population suffering from TBI. This initiative will deliver practical approaches to improving care of TBI victims in the field and beyond.